Drug Allergy Testing

Have you experienced abnormal symptoms that seemed to crop up when you took medication? Did a doctor tell you that you may have a penicillin allergy? Book an appointment with Southern California Allergy so we can help you determine whether or not you have a true drug allergy.

Diagnosis & Treatment Options

Research suggests that drug allergies are over-diagnosed, which makes a diagnosis by a highly trained allergy specialist even more critical. No one should needlessly avoid drugs that may be the best first-line treatment for a condition.

The doctor will perform a physical exam and discuss your medical and allergy history. This information will help determine which testing method(s) to utilize.

Skin testing

We offer both skin prick and intradermal (injection) tests. With the skin prick test, a drop of the medicine extract is applied using a plastic applicator to prick/scratch the skin’s surface. The intradermal test uses a small needle to inject the allergen just under the skin. Both tests require observation for raised, red, itchy bumps (called wheals). The size of the wheal generally correlates to your sensitivity to the medication. While a positive result generally indicates a drug allergy, a negative skin test does not necessarily rule out an allergy to the drug. This type of gray area is where Dr. Schulte’s depth of knowledge and experience prove invaluable.

Patch testing

Patch testing looks for delayed allergic reactions to medications. Your doctor will place a tiny amount of medication in a chamber that gets taped to your back. After 48-72 hours, you return to the office for patch removal and examination of skin results.

Oral challenge

Depending on other test results, an oral drug challenge may be up next. In this challenge, the patient ingests increasing amount of a drug until a reaction is seen or tolerance can be verified.

Penicillin testing

Many patients come into our office for testing after being told they have a penicillin allergy. Penicillin is such a useful, effective drug that confirming or ruling out this allergy can have a big impact on a patient’s medical treatment, especially considering a true penicillin allergy can cause a life-threatening anaphylactic reaction. Penicillin allergy testing includes skin prick and intradermal options, as well as an oral challenge.

We will analyze your drug allergy testing results, and most of the time, you will learn that you definitively do or do not have a drug allergy. However, the data can prove inconclusive, indicating that you might have a drug allergy. Do not despair! This provides useful information, and we are here to help you move forward with that knowledge.